Mass Spectrometry

Antibiotics are secondary metabolites produced by bacteria, fungi, or other microorganisms, as well as their synthetic analogs. The discovery, large-scale production, and clinical application of antibiotics have been major milestones in the history of medicine, saving hundreds of millions of lives.
As one of the world's largest producers and consumers of antibiotics, China faces a serious challenge from antimicrobial resistance due to the long-term irrational use of antibiotics and inadequate regulatory oversight. Drug-resistant infections have become a leading cause of mortality from infectious diseases, highlighting the urgent need for national strategic measures to prevent the emergence of new resistance and limit the spread of existing resistance, thereby safeguarding human health and ecosystem security.
Therapeutic monitoring of multiple antibiotics enables more accurate and rapid determination of drug concentrations, providing valuable guidance for safe and rational antimicrobial therapy in clinical practice.