Mass Spectrometry

Project Background

This product is intended for the determination of Vitamin A, Vitamin D (the sum of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3), Vitamin E, and Vitamin K1 in human serum. Clinically, it is used as an aid in the diagnosis of diseases caused by the accumulation or deficiency of fat-soluble vitamins, such as hypervitaminosis and growth retardation.
Fat-soluble vitamins are essential micronutrients that participate in metabolic regulation. They are indispensable organic substances required for normal physiological functions and are important active substances for maintaining human health. Although present in small amounts in the body, they are essential. Long-term deficiency of a specific vitamin may lead to physiological dysfunction and disease. Common fat-soluble vitamins include Vitamin A, Vitamin E, 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and Vitamin K1.

Vitamin A (VA) helps maintain normal vision, promotes growth and development, enhances resistance to infectious diseases, and prevents and treats xerophthalmia. Deficiency may result in night blindness, xerophthalmia, dry skin, and desquamation.
Vitamin D is a group of fat-soluble steroid derivatives with anti-rickets activity. Among them, 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 are nutritionally significant. They regulate calcium and phosphorus metabolism, promote calcium and phosphorus absorption and utilization, and support bone growth. Deficiency may lead to rickets (in children and adolescents), osteomalacia (in adults), and osteoporosis.
Vitamin E (VE), also known as tocopherol, has anti-aging, anticoagulant, and immune-enhancing effects. It improves peripheral blood circulation, helps prevent arteriosclerosis, and maintains the integrity of red blood cells, white blood cells, brain cells, and epithelial cells. Long-term deficiency may cause megaloblastic hemolytic anemia.
Vitamin K1, also known as the coagulation vitamin, primarily promotes blood coagulation and participates in bone metabolism. Deficiency may result in abnormal blood coagulation in adults, causing symptoms such as gingival bleeding, epistaxis, hematuria, gastrointestinal bleeding, and ecchymosis.
This assay kit is suitable for the determination of fat-soluble vitamin levels in the human body to assist clinicians in providing effective and appropriate vitamin supplementation. Early detection, early intervention, and early treatment are of great significance in reducing nutrition-related diseases.

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