This kit is used for in vitro quantitative determination of retinol binding protein concentration in human serum samples by medical institutions for auxiliary diagnosis.

The retinol-binding protein in the blood binds with pre-thyroxine albumin to form A complex that functions as Vitamin A delivery system. RBP combined with TBPA has a half-life of only 3.5h. The complex binds to retinol in a stable and specific manner and performs cell operation. RBP is only a carrier of retinol in plasma. Excess retinol binding proteins are filtered through the glomeruli and absorbed by the proximal convoluted tubules. A decrease in glomerular filtration rate can lead to an increase in blood RBP. In addition, liver and gallbladder system disease, parathyroidism, malabsorption syndrome can cause the RBP in the blood to reduce, while chronic kidney disease is elevated.

Serum (RBP) + reagent antibody (anti RBP sensitization of latex particles), antigen-antibody complexes, resistance of RBP in serum samples and reagents RBP antibody sensitization emulsion particles to form immune complex, turbidity, the reaction liquid by spectrophotometer at 570 nm wavelength absorbance value discretion of RBP content in serum samples.